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It acts as a primary defense against oxidative stress

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They build gradually and persist through brief interruptions

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High concentrations of copper can become toxic, since it can replace the iron in iron-sulfur clusters of proteins and damage or inactivate those proteins ( Interestingly, the mechanism behind the antimicrobial copper surfaces is different between wet- and dry-contact killing (Ramos-Ziga et al., 2023)

36-38 CURRENT GUIDELINE RECOMMENDATIONS: ROLES OF INCRETIN-BASED THERAPIES AND SGLT-2 INHIBITORS The use of currently available treatments for T2DM are guided by clinical recommendations from several organizations, including the ADA and the AACE/ACE