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This trend may favor peptide therapeutics that demonstrate superior effectiveness or safety profiles

This indicated a decrease in GAPDH activity and a concomitant diversion of glucose into the oxidative phase of the pentose phosphate pathway (PPP), a metabolic shift that, upon oxidative stress, helps restore NADPH levels and cellular reducing potential (Figure 1)

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Tan Q, Akindehin SE, Orsso CE, Waldner RC, DiMarchi RD, Muller TD, et al

With files from CBC's Alison Northcott and Marcy Cuttler

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