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Sulfiredoxin: a potential therapeutic agent

About This Test The Glutathione test measures important markers in your blood

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[DOI] [PubMed] [Google Scholar] 34.Ide C

148 Leptin limits insulin synthesis and secretion from pancreatic -cells, resulting in increased insulin sensitivity, reduced hepatic glucose production and decreased glucagon levels

This resistance is due to the upregulation of the subunits (SLC7A11 and SLC3A2) of the cystine/glutamate antiporter system x c - which imports cystine in exchange for glutamate, sustaining the production of glutathione and thus the function of GPX4 in those cells