Overall, the findings of the present study demonstrated that intra-articular stimulation of the liraglutide/GLP-1R axis has analgesic effects in vivo , which was probably due to the anti-inflammatory and anti-catabolic effects of liraglutide in vivo and in vitro, as demonstrated in vitro in macrophages and chondrocytes
These findings, in line with several recent studies reporting the protective effects of statins in various kidney diseases [42,43,44,45], underscore the critical role of lipid metabolic dysregulation in CaOx-induced renal injury and suggest that pharmacological modulation of lipid metabolism may serve as a complementary strategy to targeting the PRMT1/UBE2m axis
Association of vitamin B12 with obesity, overweight, insulin resistance and metabolic syndrome, and body fat composition
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J Neurochem 102:170178 Kiskinis E, Sandoe J, Williams LA et al (2014) Pathways disrupted in human ALS motor neurons identified through genetic correction of mutant SOD1
