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Dorr RT, Lines R, Levine N, Brooks C, Xiang L, Hruby VJ, Hadley ME

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70 As cells use NADPH to reduce cystine to cysteine, the increased cysteine catabolism by CDO implies the increased consumption of NADPH, which will affect other cell metabolic pathways and the antioxidant capacity as well

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There are no data indicating that acetylcysteine adversely influences hepatic failure, but this remains a theoretical possibility