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The growth and stable interaction of microtubules with the cell cortex is a critical contributor to frontback cell polarity that is necessary for directed cell migration [12]

One point I find powerful to add is how the mitochondria themselves respond differently depending on the fuel

Braz J Biol 81:592600 Zoeller TR, Dowling AL, Herzig CT, Iannacone EA, Gauger KJ, Bansal R (2002) Thyroid hormone, brain development and the environment

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The molecular systems involved include actin cytoskeletal remodeling and integrin signaling, with focal adhesion pathways facilitating attachment of fibroblasts to collagen