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In chronic pain and depression, morphological and functional neuroplastic changes were found most pronounced in fronto-limbic regions (Teffer and Semendeferi, 2012)

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Aside from this single case report, a RCT on the effect of a broccoli sprouts extract administration in 45 patients for 84 days demonstrated no variations in TSH, FT4, anti-TPO and anti-Tg autoantibodies positivity rate [158]

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