GLP-1/Amylin dual-therapy is a moderately concentrated market worldwide due to CagriSema being the lead program of Novo Nordisk that enjoys the first-mover advantage
103.Bays H.E., Fitch A., Christensen S., Burridge K., Tondt J
Reduced inflammation from weight loss itself may also lower anxiety-related biomarkers, creating a secondary benefit independent of direct brain receptor activation
doi: 10.1038/s41420-024-01969-6 34 WangXChenBSunJJiangYZhangHZhangPet al
Key Takeaways for Researchers# Evidence quality varies dramatically -- from Thymosin Alpha-1's 11,000+ human subjects to KPV's entirely preclinical record
Hence, this review aims to expound the pathophysiology of IBS and the influence of gut microbiome on IBS pathogenesis, and shed light on current advances and future directions in IBS research and therapeutic interventions