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These observations emphasize the value of biomarker-guided therapeutic windows for antioxidant and anti-inflammatory strategies 24

However, when the 60-plus age group gets COVID-19, their glutathione levels were much lower and oxidative stress was much higher than those of a similar age but without COVID-19. This is an important new discovery, Sekhar said

Future investigations could explore novel therapeutic avenues from the synovium and subchondral bone perspectives

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To investigate whether VRK2 directly phosphorylates Sec24C, we carried out an in vitro kinase assay and found that overexpression of VRK2 was able to increase the phosphorylation level of Sec24C

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