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When the content of ROS is too high and completely destroys the redox dynamic balance, lipid peroxidation will be induced by non-enzymatic and enzymatic pathways, and then result in ferroptosis (Su et al., 2019)

While there is some limited evidence of the efficacy of 1,000 micrograms daily dosing of oral cyanocobalamin, this is mainly based on the correction of serum vitamin B12 levels, rather than any impact on clinical signs and symptoms[24]

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[Google Scholar] 271.Kaji I, Karaki S, Kuwahara A