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10.3389/fonc.2024.1384928 133

doi:10.1136/bmj.4.5789.719 123

Nicely done

This review focuses on major depressive disorder (MDD)the most common subtype characterized by persistent low mood, loss of interest, and impairment in social/occupational functionrather than bipolar depression or situational depression, as MDD has the strongest evidence linking to dietary and gut microbiota changes (1, 4)

Every one of these is a preclinical or review paper

It was synthesized mainly through genetic engineering and other biological methods, which involved technical difficulties and high production costs and was inconducive to large-scale production