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Note: Compounded semaglutide and tirzepatide from licensed 503A pharmacies follow similar clinical frameworks as brand medications but are prescribed off-label in pediatric settings

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Retatrutide clinical trial data Retatrutide data comes primarily from two sources: a Phase 2 trial published in the New England Journal of Medicine and the Phase 3 TRIUMPH program that began reporting results in mid-2025

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Food and Drug Administration first approved GLP-1 medication to treat Type 2 diabetes in 2005

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