In addition, HGF upregulates -catenin, contributing to the repair of tight junctions and the expression of bile transporters (OATP2, BSEP, NTCP1), thereby attenuating the progression of hepatic fibrosis (Du et al., 2023
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Sunny, Parks, Browning, & Burgess, 2011), raising the question of whether NAFLD progression is accelerated by ER stress arising from this increased flux, and whether diminished hepatic TCA flux in mice lacking MPC activity protects the liver at least in part by alleviating or preventing ER stress
(Falutz 2010) Ionescu M, Frohman LA
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