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When acetylcholine (or bradykinin or adenosine) binds its receptor on the surface of endothelial cells, a signal cascade, coupled to the activation phospholipase C- (PLC), is initiated

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Specimens of fibrotic intervertebral discs were collected from five patients, two males and three females, with a combined average age of 63.4 3.74 years (5274 years)

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