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Combining the changes in the three groups, at the genus level, Clostridium_sensu_stricto_1 was increased in the TS group compared to the CON group, and GABA treatment alleviated the Clostridium_sensu_stricto_1 abnormality, suggesting a potential mechanism (Figure 2D)

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Less commonly recognized but still valid qualifying conditions include prediabetes (elevated fasting glucose or A1C between 5.7-6.4%), polycystic ovary syndrome, non-alcoholic fatty liver disease, osteoarthritis of weight-bearing joints, and chronic kidney disease

doi: 10.1136/gutjnl-2022-327909 157 XueYLuFChangZLiJGaoYZhouJet al

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