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Additionally, the large number of mutations and divergent consequences on protein structure, make a one-size fits all therapy unlikely

For example, statins are being evaluated at micromolar concentrations, whereas therapeutic doses of statins typically result in human serum concentrations ranging from 1 to 15 nM (115)

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These mechanisms are connected

[DOI] [PMC free article] [PubMed] [Google Scholar] 17.Yaribeygi H., Farrokhi F.R., Abdalla M.A., Sathyapalan T., Banach M., Jamialahmadi T., Sahebkar A

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