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Some of the key allegations in the Ozempic lawsuits include the following: Failure to warn and inadequate labeling: Lawsuits contain allegations that Novo Nordisk did not adequately warn Ozempic patients about some of the severe gastrointestinal and vision complications they might experience
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The dose starts low and increases over weeks to reduce side effects
Despite the fact that both GIP and GLP-1 levels depend on renal metabolism, and are increased in individuals with CKD and renal failure [45, 46], no relevant effects of eGFR on drug exposure were detected when assessing the pharmacokinetics of tirzepatide 5 mg in individuals with preserved renal function or various degrees of renal impairment [47]
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