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PBMCs were cultured in X-VIVO 15 medium (Lonza) with 10% (v/v) human autologous serum, AAS, 10 ng/mL macrophage colony-stimulating factor (M-CSF) and 10 ng/mL granulocyte-macrophage colony-stimulating factor (GM-CSF) (Peprotech, Hamburg, Germany) to induce macrophage differentiation

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3D), characterized by increased proximity to Stranger 1 and reduced non-social exploration

doi: 10.3389/fphar.2022.879729 Received 20 February 2022 Accepted 06 June 2022 Published 24 June 2022 Volume 13 - 2022 Edited by Jotam G