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Patients should understand that such treatments are not substitutes for evidence-based weight management strategies endorsed by NICE, including dietary modification, physical activity, andwhere appropriatelicensed pharmacotherapy

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In in vitro cell experiments using 3T3L1 preadipocytes as a model, treatment with NNMTi significantly reduced preadipocyte differentiation efficiency and markedly downregulated the expression of adipocyte markers (such as PPAR and C/EBP) in a dosedependent manner

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If you realize this mistake immediately, contact your pharmacy for guidanceyou may need to discard the vial and start fresh

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