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Although pharmacological compounds aimed at inducing ferroptosis, such as erastin and RSL3, or inhibiting it, such as ferrostatin-1 (fer-1), have demonstrated potential in preclinical studies, their application in clinical settings faces challenges, including off-target effects and limited tissue specificity [2,3,4,5,6]

Lee H, Kim H, Lee S-A, Won Y-S, Kim H-I, Inn KS, Kim B-J (2015) Upregulation of endoplasmic reticulum stress and reactive oxygen species by naturally occurring mutations in hepatitis B virus core antigen

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