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High non-ceruloplasmin-bound copper can increase oxidative stress, while low zinc may impair copper regulation and SOD1/SOD3 structure

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We also observed increased gene expression levels of Transferrin receptor 1 ( TfR1) in all four cancer cell lines relative to HThF (Fig

In some cases, this allowed reduction in dose of other medications such as insulin which they had often been taking for many years

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