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Cardiovascular safety outcome trials included patients with T2DM and either established CV disease or multiple CV risk factors (and albuminuria or impaired renal function in CARMELINA)

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Contraindications include a personal or family history of medullary thyroid carcinoma (MTC) or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2), or a history of pancreatitis

Behavioral Changes: Address emotional eating and develop healthier coping mechanisms through therapy or counseling