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TRIUMPH-8 focuses on general obesity

Less-selective compounds in the same class (GHRP-2, GHRP-6, hexarelin) cross-activate other endocrine axes alongside GH, which makes them noisier reference tools when researchers want to isolate ghrelin-pathway signalling from confounding hormonal effects

no Phase 2 or Phase 3 human safety trials have been completed

The most common side effects are nausea, decreased appetite, and mild GI discomfort, particularly during dose increases

PMC11241973 Impact of GLP-1 Receptor Agonist Therapy in Patients High Risk for Sarcopenia

Pregnant women or patients with uncontrolled medical issues (like severe asthma, active infections, or glutathione allergy) should avoid it