In diabetic cardiomyopathy, energy metabolism in cardiomyocytes may be impaired due to factors such as hyperglycemia and insulin resistance
Mitochondria, as the major site of oxidative reactions, must maintain sufficient levels of GSH to perform protective and biosynthetic functions 2
Mercury toxicity and antioxidants: Part 1: role of glutathione and alpha-lipoic acid in the treatment of mercury toxicity
Ranjan A, Ramachandran S, Gupta N, Kaushik I, Wright S, Srivastava S, et al
The incorporation of Se is mostly accredited both in selenite (oxidized form) and selenocysteine (reduced form) to sequester excess Se onto apoplastic or non-cellular spaces
Together, these findings indicate that melatonin drives ILC2s into a metabolic state incompatible with a pro-inflammatory effector phenotype