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To understand the mechanism of precocious sexual maturation following prepubertal GH therapy, the effects of rhGH on the hypothalamus-pituitary-gonad axis were examined in the immature male rats

& Warrington, R

2-4 Weeks

Trimethylamine-N-Oxide promotes osteoclast differentiation and bone loss via activating ROS-dependent NF-B signaling pathway

157 A partial explanation for the failure of the KD as a monotherapy in the ERGO trial could be based on the fact that there was no significant drop in blood glucose or HbA1c levels, and only part of the patients reached stable ketosis

Lower concentrations (5mg/ml) require larger injection volumes but offer more precise small-dose measurement