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This does not invalidate the findings, but it is a standard scientific quality consideration that most pages omit

Cecal samples Cecal weight was measured since the weight of this portion of the intestine appears to be highly influenced by the microbiome (e.g., certain antibiotic treatments dramatically increase cecal weight 27,28,29,30,31 but not the colon 27 )

Where methyl B12 shows its greatest utility is with people suffering from degenerative neurological symptoms, where its often the only promising treatment