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Pediatrics 140 , e20171305 (2017)

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The study raises the role of systemic ozone therapy in atopic asthma by means of the immunomodulatory and oxidative stress regulation properties of this therapy

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doi: 10.1056/NEJMOA1607141/SUPPL_FILE/NEJMOA1607141_DISCLOSURES.PDF 15 HolmanRRBethelMAMentzRJThompsonVPLokhnyginaYBuseJBet al

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Recommended dose: depending on the individual between 10 1000 g/day

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The half-life of COHb after exposure to MC is 13 h due to continuous metabolism

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