Apart from reward, this initial AUD phase is influenced by the motivation to consume alcohol, which is another factor controlled by GLP-1R in male rats
Back Mojsov, Svetlana emails to Lara Marks, Dec 2024, March 2025
This translated into seven fewer new substance use disorder diagnoses per 1,000 GLP-1 users
Two weeks after taking 0.5 mg, one patient reported she hadnt felt that well in a decade, was eating foods she hadnt been able to tolerate, was able to go to a restaurant again, and had even gone for a hike
Key Takeaways Ozempic and alcohol are not automatically incompatible, but the combination may affect people differently
The presence of GLP-1 receptors in these reward pathways has prompted researchers to investigate whether GLP-1 agonists might influence behaviours beyond eating, including alcohol consumption