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doi:10.1074/jbc.M510764200

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Neuroinflammatory proteins in Huntingtons disease: Insights into mechanisms, diagnosis, and therapeutic implications

Current treatment relies heavily on antibiotics, however, the rapid emergence of multidrug-resistant strains has severely compromised their efficacy, underscoring the urgent need for alternative therapeutic strategies

The hydroxyl radicals produced via copper-catalyzed Fenton reactions mediate oxidative damage, primarily by oxidizing LDL into oxidized LDL (ox-LDL), which serves as a key driver of atherosclerotic plaque formation [121]