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CV: cardiovascular The treatment effect for the primary composite endpoint, its components, and other relevant endpoints in Study 1 are shown in Table 6
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The studies presented in this work that show superiority of SMG over other GLP-1 receptor agonists are funded by Novo Nordisk, and the studies [153,178] that show tirzepatides superiority over SMG are funded by Eli Lilly, Novo Nordisks American rival in the formulation of GLP-1 receptor agonist drugs
Jan has "no regrets" and still describes the drug as the "best thing that ever happened to me"
Semaglutide addresses multiple lipid parameters simultaneouslylowering LDL, reducing triglycerides, and raising HDLwithout the same adverse effect profile as some statin therapies
Factors influencing this decision include: GI sensitivity Blood sugar control needs Medication half-life I personally have seen patients switch without the need for a washout period except for on rare occasions when they experience severe side effects from semaglutide Potential Benefits of Switching to Tirzepatide Potential Benefits of Switching to Tirzepatide Switching from semaglutide to tirzepatide may offer several potential benefits, especially for individuals who havent achieved their target weight or glycemic control
