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Matsumoto T, Harada N, Azuma M, Chihara Y, Murase K, Tachikawa R, Minami T, Hamada S, Tanizawa K, Inouchi M, et al

D1 receptors blockade stereospecifically impairs the acquisition of drug-conditioned place-preference and place-aversion

The applicant used the Assessment Aid to facilitate the FDAs review

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However, the authors included unpublished data from gray literature in Chinese, which is not accessible to individuals outside China

This is why stopping the medication during the early adjustment period (often the first month or two), when side effects are at their worst, often means missing the window in which the body would naturally adapt