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Beyond iron buffering, GSH supports biosynthesis and maintenance of Fe-S clusters, essential cofactors for mitochondrial respiratory enzymes 15

This ratio is based on preclinical models of wound healing and regenerative research

doi: 10.1016/j.cld.2018.12.006

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143,144,145,146 In this study, a mouse 3T3-L1 fibroblast based in vitro models indicated that, apart from elevated glucose uptake and lactate release, proliferating fibroblasts showed improvements in mitochondrial respiration as well as coupling efficiency

CV, cardiovascular