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Free heme has also been shown to promote inflammatory gene transcription in macrophages via TLR4 and NLRP3 inflammasome signaling, which have both been implicated in worsened atherosclerosis 72,73,74,75 (Fig

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miR-6852, which is regulated by lncRNA linc00336, can inhibit lung cancer progression by promoting ferroptosis

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Notably, deferred frozen-thawed embryo transfer (FET) may restore synchrony and reset the uterine environment, with studies reporting higher live birth rates and lower miscarriage rates compared to fresh transfer, though clinical routine use requires caution due to heterogeneity in evidence