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Furthermore, microcrystalline urate deposition activates the NLRP3 inflammasome in renal and vascular tissues, exacerbating kidney disease and cardiovascular complications through IL-1-mediated inflammation (Wang Q

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Additionally, snail egg production decreased when exposed to ibuprofen (p = 0.001) but increased when exposed to microplastics (p = 0.002)

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Dysbiosis-induced circadian disruptions have been implicated in sleep disturbances, mood disorders, and metabolic dysfunctions [165, 166]