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It's not because these medications directly affect muscle tissue

PMID: 40141334

Intraneuronal beta-amyloid aggregates, neurodegeneration, and neuron loss in transgenic mice with five familial Alzheimers disease mutations: potential factors in amyloid plaque formation

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However, the long-term cardiovascular and renal benefits need to be carefully evaluated against the risk of DKA

Age, gender, exercise, weight, pregnancy, diet, and medications can all influence GGT levels in the body [8, 9, 10]