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Understand The Dosage Requirements Your prescriber will set the exact starting dose and titration schedule based on your medical history, weight, and treatment goals

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doi:10.1007/s40262-017-0528-2 38

However, if severe vomiting or diarrhea occurs, temporary additional contraceptive methods may be advisable, as with any medication that might cause significant gastrointestinal disturbance

95% CI 1.112.78)