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Fc fusion to glucagon-like peptide-1 inhibits degradation by human DPP-IV, increasing its half-life in serum and inducing a potent activity for human GLP-1 receptor activation
A BMI at or above the 95th percentile for age and sex, based on standardized growth charts, is considered obese
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Rushing through titration means stacking the side effect peaks from multiple dose increases, which increases the likelihood of nausea, anxiety , and other unwanted responses that might have resolved with patience