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The most common causes of sudden onset are post-inflammatory hyperpigmentation from a minor injury (biting, burning food, allergic reaction to a product), a small blood blister or hematoma from trauma, or a venous lake forming under the surface

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doi: 10.1038/s12276-020-0408-y 78

Cancer 18, 619633

Photo: Getty Images June 2, 2026 Results of an American College of Radiology-managed retrospective study involving 110,000 women presented at the 2026 ASCO Annual Meeting, shows that those who took GLP-1 medications were up to 35% less likely to develop breast cancer than those who did not take GLP-1 drugs