Nonetheless, it should be used within a certain timeframe as recommended by the pharmacy (often 28 days after first puncture, per general guidelines for multi-dose vials, unless otherwise specified)
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Rotate injection sites weekly to prevent lipodystrophy (changes in fat tissue under the skin)
Histologically there is presence of T lymphocytes, B lymphocytes, macrophages and mast cells in the synovial membrane and fluid compartment
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