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The synergistic insulin secretion produced by simultaneous GIP and GLP-1 receptor activation is mechanistically distinct from what amylin/GLP-1 combinations provide, and the SURPASS trial data in diabetic populations is among the strongest in the field

10.1016/j.arr.2021.101304 50 HuR.LuoH.JiY.WangZ.ZhengP.OuyangH.et al (2023)

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