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17 Noguchi , Y., & Wroth, C

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For example, the neurotoxin models of PD (using MPTP or 6-OHDA) recapitulate features of the diseaseelevated -synuclein, astrocyte activation, bloodbrain barrier disruption, inflammation, oxidative stress, and dopaminergic neuron lossand these models have demonstrated the neuroprotective potential of various dietary polyphenols (10)