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The trajectory matters more than any single data point

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In clinical trials, patients taking Mounjaro lost an average of 15-22% of their body weight [3] , making it one of the most effective medications for weight management currently available [4]

However, many FRGs identified by bioinformatics remain to be verified experimentally

The upregulation of ThDP-dependent DHTKD1 protein 69 months after the gastric bypass surgery (Figures 4B, 5B) is similar to the long-term increase of DHTKD1 protein observed after another type of surgical intervention (laminectomy) (48)