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Posadzki PP, Bajpai R, Kyaw BM, Roberts NJ, Brzezinski A, Christopoulos GI, et al

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In T2DM with obesity, adipose tissue becomes dysfunctionalcharacterized by adipocyte hypertrophy, altered extracellular matrix (ECM) remodeling, immune cell infiltration, and impaired mitochondrial functionthereby promoting insulin resistance and systemic metabolic deterioration [1]