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Chronic copper overload is a potent driver of pathological cardiac remodeling, primarily by inducing sustained oxidative stress

In the elderly, physiological senescence could reduce RXR-

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The triangular fibrocartilage is a meniscus-like structure composed predominantly of type I collagen

The Scandinavian PROLONG (PROtective genetic and non-genetic factors in diabetic complications and LONGevity) initiative in Sweden and Denmark was launched aiming to identify clinical, metabolic and genomic factors promoting protective mechanisms in individuals with long-term T1D who have escaped from the development of diabetic complications