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Alanine scanning studies have identified specific amino acids, including His7, Gly10, Phe12, Thr13, Asp15, Phe28, and Ile29, that play crucial roles in receptor binding and activation

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Warnings and Precautions for Alli Do not take Alli if you: Are pregnant or breastfeeding Have chronic malabsorption syndrome or cholestasis Are taking ciclosporin or warfarin (unless supervised) Have certain kidney problems Use caution if you: Have diabetes, kidney disease, epilepsy, thyroid disorders, HIV, heart rhythm problems, or take medicines for psychiatric disorders Use hormonal contraceptives (consider extra contraception if severe diarrhoea occurs) Take medicines for high blood pressure or cholesterol Important: Take a multivitamin containing vitamins A, D, E, and K at bedtime while using Alli

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Patients with severe blockages may be unable to work or return to normal activities as a result of the condition

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