who invented tirzepatide Tirzepatide, a New Era of Dual-Targeted Treatment for Diabetes and Obesity: A Mini-Review Republican Administration Maintains Exclusivity Stance

The move follows a June 2023 announcement by the American Society of Anesthesiologists (ASA) that suggested withholding GLP-1 ra before elective surgery to reduce the risk of complications associated with anaesthesia in adults and children

SURMOUNT-OSA Study 2 evaluated tirzepatide in adults with moderate-to-severe OSA and obesity who were on and planned to continue to use PAP therapy for 52 weeks

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On side effects: GI events were somewhat higher in the tirzepatide arms at the highest doses, consistent with a stronger gastric-emptying effect from the dual GIP and GLP-1 mechanism