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Plan accordingly, and the data will follow

Protocol compliance: Consistent dosing and proper storage maximize results

However, previous results indicate that the number of significantly altered metabolites in HepaRG exposed to -pyrrolidinobutiophenone (-PBP) and -pyrrolidinoheptaphenone (-PEP) is lower that in human liver microsomes (HLM) or PHHs

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Because the half-life is short, skipping doses leaves gaps in the metabolic signal youre trying to build

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