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Based on an AtSOT1 structural model generated by alphafold, both cysteines are too far away for predicting any redox regulation mechanism involving an intramolecular disulfide

3.8 GQD inhibits the expression of TNF-, IFN- and IL-17 proteins in the colon of UC mice To experimentally validate the inflammatory regulatory mechanism of GQD, immunohistochemistry (IHC) was used to assess whether GQD suppresses the colonic expression of key pro-inflammatory cytokines

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Environ Health Perspect, 49, 59-69