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A: Yes, it is recommended to consult with your healthcare provider before starting any new dietary supplement, especially if you have pre-existing medical conditions, are pregnant or breastfeeding, or are taking other medications

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Histological evaluation followed established methodologies, including the NAFLD Activity Score (NAS) for grading steatosis, inflammation, and hepatocellular ballooning, and the NASH Clinical Research Network (CRN) fibrosis staging system for quantifying fibrosis severity

It's important to note that a higher-dose formulation of semaglutide (2.4mg), marketed as Wegovy, has been specifically licensed for weight management, with clinical trials showing weight loss of approximately 10-15%

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Metabolomics 8 , 253263, (2012)