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This relationship exists partly because excess weight triggers chronic low-grade inflammation, elevates stress hormones like cortisol, and disrupts sleep architectureall factors that amplify anxiety

Arijit Chowdhury Board Certified Internal Medicine Internal Medicine, Pulmonary & Critical Care Tynetta Eleazer MSN, RN, APRN, FNP-BC Nurse Practitioner Long-term well-being requires addressing both physical and mental health

10.2337/diabetes.50.3.609 191 WaughN.CumminsE.RoyleP.ClarC.MarienM.RichterB.et al (2010)

Kim JS, Wilson JM, Lee SR

Vitamin B12 helps to boost metabolism, aiding in the efficient breakdown of fats and proteins

Another important variable to consider, that this retrospective study was not able to fully assess, is the allostatic load